Ascorbic acid and nitrosamine
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چکیده
منابع مشابه
Accelerating effect of ascorbic acid on N-nitrosamine formation and nitrosation by oxyhyponitrite.
The reaction of nitrite ion with ascorbic acid and its effect on the rate of nitrosation of secondary amines have been investigated by differential pulse polarography in aqueous acidic solution. Ascorbic acid shows nonuniform behavior: it accelerates the nitrosation of N-methylaniline between pH 1.00 and 1.95, allows the nitrosation of diphenylamine and iminodiacetonitrile, but inhibits the nit...
متن کاملEvaluation of the protective effect of ascorbic acid on nitrite- and nitrosamine-induced cytotoxicity and genotoxicity in human hepatoma line.
Nitrites are ubiquitous environmental contaminants present in drinking water and foods. Nitrosamines can be formed endogenously from nitrate and nitrite and secondary amines or may be present in food, tobacco smoke, and drinking water. The major goal of this work was to evaluate the cytotoxic, reactive oxygen species (ROS)-producing and genotoxic effects of nitrite and nitrosamines and the poss...
متن کاملAscorbic Acid and Cozymase
Virtanen, A. I. & Hietala, P. K. (1955b). Acta chem. scand. 9, 549. Virtanen, A. I. & Kari, S. (1954). Acta chem. 8cand. 8, 1290. Virtanen, A. I. & Kari, S. (1955). Acta chem. 8cand. 9, 170. Virtanen, A. I. & Linko, P. (1955). Acta cUem. 8cand. 9, 551. Virtanen, A. I., Uksila, E. & Matikkala, E. J. (1954). Acta chem. 8cand. 8, 1091. Vogel, H. J. (1953). Proc. nat. Acad. Sci., Wa8h., 39, 578. Vo...
متن کاملAscorbic Acid and Alloxan
Since it is known that alloxan will react with many substances, and because preliminary unpublished work in this laboratory suggested that ascorbic acid potentiated the action of alloxan, the effect of ascorbic acid on the diabetogenic action of alloxan was investigated. Experimental. Hooded rats weighing approximately 250 g were used in this study. These animals were fed Purina Dog Chow during...
متن کاملAscorbic Acid Dehydroascorbic Acid C6 Dicarboxylic Acid
Dehydroascorbic acid is shown to be converted to 2-(threo-l,2,3-trihydroxypropyl)tartronic acid in aqueous alkaline solutions. The structure of the acid was determined by mass spectrometry of its acyclic Me3Si derivative. Mass spectrometric and chromatographic data are compared with those of related compounds. The acid is formed by a benzilic acid rearrangement of the intermediate 2,3-hexodiulo...
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ژورنال
عنوان ژورنال: Nature
سال: 1974
ISSN: 0028-0836,1476-4687
DOI: 10.1038/250684a0